Research Peptide Blog
In-depth articles grounded in peer-reviewed literature. We write about what the science actually shows -- including where evidence is strong, preliminary, or conflicting.
Showing 35 articles
Research Chemicals for Metabolic Studies: 2026 Guide
Complete guide to research chemicals and peptides for metabolic studies in 2026. Compound profiles, mechanism comparisons, protocol design, and sourcing information.
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AOD-9604 vs Semaglutide: Metabolic Research Compared
Comparing AOD-9604 and semaglutide for metabolic research. Different mechanisms, evidence levels, and research applications for hGH fragment vs GLP-1 agonist.
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Semaglutide vs Tirzepatide: Research Comparison 2026
Head-to-head comparison of semaglutide and tirzepatide for metabolic research. Receptor profiles, clinical trial data, mechanism differences, and compound selection.
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Weight Loss Peptides for Research: What Science Shows (2026)
Evidence-based ranking of metabolic research peptides in 2026. AOD-9604, GLP-2 TZ, GLP-3 RT, 5-Amino-1MQ, SLU-PP-332, and MOTS-c compared by mechanism and data.
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Retatrutide (GLP-3 RT): Triple Agonist Research Profile
Comprehensive research profile of retatrutide, the GLP-1/GIP/glucagon triple receptor agonist. Phase 2 data, mechanism of action, and research compound guide.
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Semaglutide Research: Mechanism, Studies & Literature Review
Complete semaglutide research guide covering GLP-1 receptor binding, STEP trial outcomes, pharmacokinetics, and preclinical mechanism data for laboratory use.
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GLP-1 vs GLP-2 vs GLP-3: Complete Research Comparison (2026)
A comprehensive comparison of GLP-1, GLP-2, and GLP-3 receptor agonists for research. Mechanisms, binding profiles, clinical data, and compound selection guide.
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The SIRT1-NAD+ Axis: A Key Target in Peptide Longevity Research
How the SIRT1-NAD+ signaling axis connects cellular energy, aging, and peptide interventions like NAD+ supplementation and MOTS-c.
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CJC-1295 + Ipamorelin: The Combination Research Protocol
Why CJC-1295 and Ipamorelin are combined in research — complementary receptor targets, synergistic GH release, and study design considerations.
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GLP-3: Next-Generation Metabolic Peptide Research
What researchers need to know about GLP-3 receptor agonist compounds — the newest addition to the incretin-based metabolic research toolkit.
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GLP-2: The Intestinal Growth Factor in Metabolic Research
Research review of GLP-2 — the incretin hormone studied for intestinal epithelial growth, nutrient absorption, and gut barrier function.
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Reading PubMed: A Researcher's Guide to Peptide Literature
How to search, evaluate, and interpret PubMed articles on research peptides. Search strategies, study quality assessment, and citation analysis.
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The Future of Metabolic Peptide Research
Where metabolic peptide research is heading — oral formulations, multi-receptor agonists, mitochondrial targets, and the convergence of obesity and aging science.
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AI and Peptide Discovery: How Machine Learning Is Changing Research
How artificial intelligence is accelerating peptide discovery — from AlphaFold structure prediction to generative sequence design and activity prediction.
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Growth Hormone Releasing Pathways: GHRH vs GHS-R Mechanisms
Two pathways, one outcome: how GHRH receptor and ghrelin receptor (GHS-R) signaling converge on growth hormone release, and why combining them matters.
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Mitochondrial-Targeted Peptides: The Next Research Frontier
MOTS-c, SS-31, and the emerging class of mitochondria-targeted peptides. How they work, what they target, and why mitochondrial medicine is growing.
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Essential Peptides for Anti-Aging and Longevity Research
The most studied peptides in aging research — Epitalon, NAD+, MOTS-c, GHK-Cu, and SS-31. Mechanisms, evidence levels, and how they target aging hallmarks.
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Growth Hormone Secretagogues: A Complete Research Guide
Everything researchers need to know about GH secretagogues — Ipamorelin, CJC-1295, GHRP-6, Tesamorelin, and how they differ in mechanism and selectivity.
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Understanding Mass Spectrometry in Peptide Analysis
How mass spectrometry confirms peptide identity — ESI-MS, MALDI-TOF, and what molecular weight data means on your COA.
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Understanding Preclinical vs Clinical Peptide Research
The pipeline from preclinical discovery to clinical trials — what each phase means, why most peptides are preclinical-only, and how to evaluate evidence levels.
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5-Amino-1MQ vs SLU-PP-332: Metabolic Research Compounds Compared
Comparing 5-Amino-1MQ (NNMT inhibitor) and SLU-PP-332 (ERR agonist) — two different approaches to metabolic and exercise mimetic research.
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NAD+ vs MOTS-c: Mitochondrial Support Compounds Compared
Comparing NAD+ (direct coenzyme supplementation) and MOTS-c (mitochondrial signaling peptide) for metabolic and aging research applications.
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What Is NAD+? Cellular Energy and Sirtuin Pathway Research
Deep dive into NAD+ — the essential coenzyme for 500+ enzymatic reactions, sirtuin activation, and mitochondrial function in aging research.
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What Is SLU-PP-332? The Exercise Mimetic ERR Agonist
Research review of SLU-PP-332 — an ERR agonist studied for mitochondrial biogenesis, endurance-related gene expression, and exercise mimetic effects.
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What Is Tesamorelin? GHRH Analog Research Review
Research review of Tesamorelin — the synthetic GHRH analog studied for growth hormone secretion and visceral adipose tissue reduction.
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What Is SS-31 (Elamipretide)? Mitochondria-Targeted Peptide Research
Research review of SS-31 — the cardiolipin-stabilizing peptide studied for mitochondrial bioenergetics, cardiac function, and age-related mitochondrial decline.
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What Is 5-Amino-1MQ? The NNMT Inhibitor in Metabolic Research
Research review of 5-Amino-1MQ — a selective NNMT inhibitor studied for NAD+ salvage pathway effects, energy metabolism, and adipocyte differentiation.
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What Is AOD-9604? Growth Hormone Fragment Research
Research review of AOD-9604 — the hGH fragment 176-191 studied for lipolytic activity without IGF-1 elevation or glucose effects.
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Peptide Research Trends to Watch in 2026
The five biggest trends shaping peptide research in 2026 — from GLP-1 agonist evolution to mitochondrial peptides, AI-driven discovery, and the post-Peptide Sciences landscape.
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NAD+ and Longevity: What the Latest Research Shows
A review of NAD+ in aging and longevity research — sirtuin activation, mitochondrial function, and why NAD+ decline is considered a hallmark of aging.
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GLP-1 Receptor Agonists: The Hottest Research Category in 2026
Why GLP-1 receptor agonists are dominating peptide research. From semaglutide to tirzepatide to next-gen compounds, we cover mechanisms, research trends, and sourcing.
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AMPK Activation: The Metabolic Switch in Peptide Research
How AMPK — the master metabolic sensor — connects exercise, fasting, and metabolic peptides like MOTS-c and 5-Amino-1MQ. A pathway guide for researchers.
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MOTS-c: The Mitochondrial Peptide Reshaping Metabolic Research
Research review of MOTS-c — the mitochondria-derived peptide studied for AMPK activation, exercise mimetic effects, glucose homeostasis, and aging research.
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Epitalon: Telomerase Activation and Longevity Research
Research review of Epitalon (Epithalon) — the synthetic tetrapeptide studied for telomerase activation, pineal gland function, melatonin production, and cellular aging pathways.
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Ipamorelin: The Selective Growth Hormone Secretagogue
Research review of Ipamorelin — the highly selective GHS-R agonist studied for growth hormone release without significant effects on cortisol, prolactin, or appetite.
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